dataframe column in list

df[df['Your_Column'].isin([3, 6])]

In [1]: df = pd.DataFrame({'A': [5,6,3,4], 'B': [1,2,3,5]})

In [2]: df
Out[2]:
   A  B
0  5  1
1  6  2
2  3  3
3  4  5

In [3]: df[df['A'].isin([3, 6])]
Out[3]:
   A  B
1  6  2
2  3  3

df[~df.isin(subset).iloc[:,0]]