how to remove all characters from a string in python

for char in line:
    if char in " ?.!/;:":
        line.replace(char,'')

s = 'abc12321cba'

print(s.replace('a', ''))

string = 'Hello WorldR'
# Lets say for instance you want to remove the R to display
# Hello World

print(string[:-1]) 
"""
The [:-<number of chars>] to remove from string starting from
right to left
"""

example_string = "Hello there"

def remove_chars(n, string):
    list_of_chars_in_string = [char for char in string] 
    
    for num in range(n):
        list_of_chars_in_string.pop() # Removes last n characters in string
    
    new_string = ''.join(list_of_chars_in_string)
    return new_string