import pandas import numpy x = numpy.array([[85, 86, 87, 88, 89], [90, 191, 192, 93, 94], [95, 96, 97, 98, 99], [100,101,102,103,104]]) row_labels = ['Z', 'Y', 'X', 'W'] column_labels = ['A', 'B', 'C', 'D', 'E'] df = pandas.DataFrame(x, columns=column_labels, index=row_labels)