remove character at index from string javascript

//replaces the first occurence only.
string.replace('characterToReplace', '');
or 
// first parameter is regular expression and g is global prop, replaces all occurences.
string.replace('/regex/g','');

// removing char at index 3
var str = "Hello World";
str = str.slice(0, 3) + str.slice(4);

console.log(str)  // Helo World

// First find the substring of the string to replace, then replace the first occurrence of that string with the empty string.

S = S.replace(S.substring(bindex, eindex), "");

//Another way is to convert the string to an array, splice out the unwanted part and convert to string again.

var result = S.split("");
result.splice(bindex, eindex - bindex);
S = result.join("");