__dopostback

<input type="button" id="btnSave" onclick="javascript:SaveWithParameter('Hello Michael')" value="click me"/>

<script type="text/javascript">
function SaveWithParameter(parameter)
{
  __doPostBack('btnSave', parameter)
}
</script>

public void Page_Load(object sender, EventArgs e)
{
  string parameter = Request["__EVENTARGUMENT"]; // parameter
  // Request["__EVENTTARGET"]; // btnSave
}